Steven T. DeKosky, MD, FACP, FANA, FAAN

McKnight Brain Institute

Dr. Steven DeKosky is the Aerts-Cosper Professor of Alzheimer’s Research at the University of Florida College of Medicine, and is Deputy Director of the McKnight Brain Institute, positions to which he was appointed in July 2015. He also serves as Associate Director of the National Institute of Aging-funded 1Florida Alzheimer’s Disease Research Center at UF. His academic appointment is as Professor of Neurology in the UF College of Medicine, and he holds joint appointments in the Departments of Neuroscience and Aging and Geriatric Research.

 

From 2008 to 2013 Dr. DeKosky was Vice President and Dean of the University of Virginia School of Medicine and was the James Carroll Flippin Professor of Medical Science; he also served as Physician-in-Chief of the University of Virginia Health System. Following his 5-year term as VP/Dean at UVA, he did a sabbatical, first as a Visiting Scholar in the Department of Medical Ethics and Health Policy at the University of Pennsylvania Perelman School of Medicine, then as Visiting Proessor of Radiology (PET Laboratory) at the University of Pittsburgh/UPMC. He is now Professor of Neurology Emeritus in the University of Virginia School of Medicine, as well as Adjunct Professor of Neurology at the University of Pittsburgh School of Medicine.

 

He received a bachelor’s degree in psychology from Bucknell University and did graduate work in neuroscience and psychology and received his MD from the University of Florida College of Medicine in 1974. He completed an internship in internal medicine at The Johns Hopkins Hospital and a residency in neurology at the University of Florida, and then was a Postdoctoral Fellow in Neurochemistry at the Clinical Neuroscience Research Center at the University of Virginia. He was on the faculty of the University of Kentucky College of Medicine from 1979 to 1990, where he co-founded the Alzheimer’s Disease Research Center and was interim chair of the department of neurology from 1985 to 1987.

 

In 1990 he moved to the University of Pittsburgh as Professor of Psychiatry (primary) and Neurology, and from 1992-2000 was Director of the Division of Geriatrics and Neuropsychiatry at Western Psychiatric Institute and Clinic, In this position he oversaw two 26 bed Geriatic Psychiatry Inpatient Units and a 12 bed neuropsychiatric inpatient unit, as well as an integrated Geriatric Medicine-Geriatric Psychiatry Outpatient Clinic, the Benedum Geriatric Clinic. In 2000 he became Professor and Chair of the University of Pittsburgh Department of Neurology, a position which he held until he moved to the University of Virginia in 2008. Dr. DeKosky was Director of Pitt’s NIH-funded Alzheimer’s Disease Research Center (ADRC) from 1994-2008. During his tenure as Chair, the Pitt Department of Neurology moved from 26th to 8th in the nation in NIH rankings for Neurology Departments.

 

His basic research centers on structural and neurochemical changes in human brain in aging and dementia and effects of traumatic brain injury (TBI). His clinical and translational research have centered on understanding the genetics, neuropsychiatric symptoms, neuroimaging, and treatment and prevention of AD. He began brain trauma studies as a Principal Investigator in the University of Pittsburgh Brain Trauma Research Center in 1992, studying similarities in the injury cascades of TBI and AD. He was an author and prime mover, with Bennet Omalu, of the first reports of Chronic Traumatic Encephalopathy (CTE) in American professional football players. He was also Principal Investigator of the program project grant studying the clinical application of the breakthrough amyloid-imaging agent Pittsburgh Compound B (PiB), for which he also held the IND (no financial interest in the compound).  He directed an 8 year NIH-funded national multicenter trial to assess whether Ginkgo biloba could prevent or delay onset of dementia in normal elderly adults, the first large study of prevention of dementia/AD.

 

Dr. DeKosky has served on and led numerous NIH review and advisory committees, and taught and mentored in clinical research training programs sponsored by the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS). He was a member of the FDA Peripheral and Central Nervous System Drugs Advisory Committee from 2004-2007 and continues to serve as an advisor to the FDA PCNS Committee.  In 2010 he was appointed to the National Advisory Council of the National Center for Complementary and Alternative Medicine (now the National Center for Complementary and Integrative Health) of the NIH. Following that term, he was appointed to the NIH’s Council of Councils from 2013 to 2015; the Council of Councils oversees the Common Fund of the NIH. Most recently he chaired the Study Section that reviewed the 2016 applications for NIA-funded Alzheimer’s Disease Centers.

 

Dr. DeKosky was a member of the national Board of Directors of the Alzheimer’s Association from 1994 to 2002 (Board Vice Chair in 2001-2002), and again from 2003 to 2010. He chaired the Association’s Medical and Scientific Advisory Council (MSAC) from 1997 to 2002. He is a former member of the Board of Directors of Alzheimer’s Disease International (ADI), the international organization of national Alzheimer’s Associations, and is now a member of the ADI Medical and Scientific Advisory Panel, a group he chaired from 2003-2006. He also serves on the National Advisory Board for the Center for Humanities, Compassionate Care, and Bioethics at SUNY-Stony Brook.

 

Dr. DeKosky served as Chair of the Section on Geriatrics of the American Academy of Neurology (AAN), and chaired the AAN Practice Parameters Committee for Early Detection, Diagnosis and Management of Dementia.

 

In 2003 he was elected to the Neurology Council of the American Board of Psychiatry and Neurology (ABPN); in 2010 he was elected President of the Neurology Council and Vice President of the ABPN. He continues to chair the ABPN’s Part B (Behavioral Neurology, Neuropsychology, and Psychiatry) Examination Committee. While holding lifetime certification in Neurology, he passed the ABPN Neurology Re-Certication examination (good for 10 years) in 2004 and again in 2015.

 

Dr. DeKosky has received the Rita Hayworth Award from the Alzheimer’s Association and the Ronald and Nancy Reagan Research Institute Award for his contributions to research and advocacy on behalf of people with Alzheimer’s disease and their families. In 2008 he received the Zaven Khachaturian Award from the Alzheimer’s Association International Conference for his contributions to Alzheimer’s disease research. In 2006 he lectured at the NIH Clinical Center in the NIH’s Great Teachers series.

 

He is the founding Chair of the Advisory Council of the International Society to Advance Alzheimer’s Disease Research and Treatment (ISTAART). He lectures nationally and internationally on multiple dimensions of Alzheimer’s Disease, including the cognitive, neurobehavioral, genetic, imaging, and basic research underpinnings of the disease.

 

Dr. DeKosky is a frequent commentator on Alzheimer’s disease and brain aging for the press and is a frequent lecturer on AD nationally. He has testified multiple times before U.S. Senate Committees for greater research funding for Alzheimer’s disease, and has met with government officials in other countries as a consultant and advocate for programs and support for people with dementia. He has received a Teacher Investigator Development Award from the NINDS, the Presidential Award of the American Neurological Association, and has been listed continuously in "The Best Doctors in America" and “America’s Top Doctors” for over a decade. He has published over 500 peer-reviewed articles and book chapters, is an associate editor for Neurotherapeutics, Current Opinion in Neurology, and Alzheimer’s & Dementia: Translational Research and Clinical Interventions, and serves on the editorial boards of several leading neurology and Alzheimer's journals and is a reviewer for multiple other journals. He is a Fellow of the American College of Physicians, the American Academy of Neurology, and the American Neurological Association

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