Behavioral Neurology

Date/Time: Tuesday, October 6, 2020 - 3:00 PM – 5:00 PM
Track: Special Interest Group
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Selective neuronal vulnerability is a defining feature of neurodegenerative illness, but why these diseases target specific neuron types within specific brain regions remains uncertain. For some neurodegenerative syndromes, even the initial neuronal targets themselves have yet to be identified. In this SIG, we will explore the neuron types targeted early in several major neurodegenerative disorders and will discuss how this information is guiding the search for disease mechanisms.


  • Understand the distinction between neurodegenerative disease and syndrome and the relationship of each concept to the underlying neuroanatomical structures involved.

  • Understand the characteristics of neuron types targeted in some of the major neurodegenerative syndromes.

  • Appreciate the distinction between selective vulnerability to disease onset and anatomically driven disease spread.


Autopsy Correlations of Flortaucipir and Pittsburgh Compound B Pet in Frontotemporal Lobar Degeneration

Early Involvement of Amygdala in Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)

Eye Movements Abnormalities as Early Biomarker of Alzheimer’s Disease: An Ecological Approach

Lesion Network Mapping of Mania Symptoms Caused by Focal Brain Lesions

Selective Vulnerability in Frontotemporal Dementia

The Upper Motor Neurons with TDP-43 Pathology Display Distinct Cellular Defects