Schedule at a Glance
Note: All session times in the Advance Program, Schedule at a Glance, and Program Index are listed in Eastern Daylight Time.
Friday, October 2, 2020
11:00 AM – 4:45 PM
ANA-NINDS Career Development Symposium
(by invitation only)
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(by invitation only)
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6:00 PM – 7:00 PM
Translational and Clinical Research Course (TCRC) Reception
This event is for pre-registered TCRC attendees only.
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This event is for pre-registered TCRC attendees only.
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Saturday, October 3, 2020
10:00 AM – 3:00 PM
10:00 AM – 6:00 PM
Translational and Clinical Research Course (TCRC)
Additional registration fee required. Registration for this program has closed.
Additional registration fee required. Registration for this program has closed.
- Clinical and Translational Research in Stroke: Model for Innovation and Technology in Design and Conduct
- Conducting Translational Research in Academia
- Development of Neurological Therapies: Update from 30,000 Feet
- Innovations in Design of Clinical Investigations and Trials
- Keys to Getting Funded Without a K
- Leading and Utilizing the CTSI
- Starting and Developing a Successful Career as a Clinical Trialist
- The Intramural NIH Research Experience
- The Path to Achieving K-Level Funding
- Treatments and Guidelines: Paths to Clinical Application
- Trial Innovation Networks and Multisite Research
7:00 PM – 8:00 PM
Sunday, October 4, 2020
8:00 AM – 9:00 PM
10:00 AM – 12:15 PM
Presidential Symposium: Leveraging Digital Technologies*
- Deep Phenotyping of Parkinson's Disease Using Digital Technology
- Developing Novel Outcome Measures for Clinical Trials
- Digital Therapeutics
- High-Performance Digital Biomarkers: Ethomic Markers for Rapid, Precise Monitoring of Disease Progression
- Patient Travel for Neurologist Visits and Implications for Telemedicine: A US Population-based Medicare Study
- Precision Rehabilitation Strategies for Motor Recovery Post Stroke
12:30 PM – 2:30 PM
Derek Denny-Brown Young Neurological Scholar Symposium
- Aging, Lysosomes and Neurodegenerative Disease
- Cerebellar Circuitry of Essential Tremor
- Dietary Weight Loss May Halt Progression of Polyneuropathy in Patients With Obesity
- Functional Genomics of Alzheimer's Disease
- Improving the Diagnostic Precision in Autoimmune Myelopathies and Their Mimics
3:00 PM – 4:00 PM
Emerging Scholar Lectures 1 (NEW!)
- An Undiagnosed White Matter Disorders Neurogenetics Clinic
- Loss of Chchd2 and Chchd10 Activates Oma1 Peptidase to Disrupt Mitochondrial Cristae Phenocopying Patient Mutations
- Objective Dystonia Identification Helps Elucidate Dystonia Pathophysiology
- The Power of Single Cell Technologies; from T Cell Receptor to Antigen(s) in Multiple Sclerosis
4:30 PM – 6:30 PM
Targeting Glia for Therapy: Mediators of Neuroinflammation, Degeneration and Repair
- Glia-Mediated Mechanisms of Chemotherapy-Related Cognitive Impairment
- Kv1.3 Channel Expressing Brain Myeloid Cells are a Unique Pro-inflammatory Subset of Microglia Which Can be Modulated by Kv1.3 Blockers in Alzheimer’s Pathology
- Oligodendrocyte Precursor Cell Present Antigen and are Cytotoxic Targets in Inflammatory Demyelination
- Single Nuclei Transcriptomic Profiling of Human Astrocytes in Alzheimer’s Disease and Aging
- Targeting Microglia-Mediated Synapse Elimination for Therapeutic Intervention in Demyelinating Disease
7:15 PM – 9:00 PM
Monday, October 5, 2020
8:00 AM – 7:30 PM
10:00 AM – 12:00 PM
Genomics of Personalized Medicine
- CRISPR-Mediated Therapeutics for Duchenne Muscular Dystrophy
- Genetic Discovery and Translation in Neuromuscular Diseases
- Genomic Approaches Paving the Way for Precision Neurology
- Patient-Customized Antisense Therapies for Rare Neurogenetic Diseases
- Towards Primary Prevention of Genetic Prion Disease
12:15 PM – 1:45 PM
2:00 PM – 3:00 PM
Emerging Scholar Lecture 2 (NEW!)
- Chemically Patterned Hydrogel Scaffolds Provide Cell-assembled Matrices to Guide Spinal Cord Regeneration
- FTH1De Novo Dominant Variants Alter Iron Metabolism and Cause a Pediatric Onset Neuroferritinopathy
- Neuropathy-causing TRPV4 Mutations Disrupt TRPV4-RhoA Interactions and Impair Cytoskeletal Regulation
- Schwann Cells with Fig4 Deficiency are Predisposed to Demyelination
3:00 PM – 3:30 PM
3:30 PM – 5:45 PM
Microenvironment Control of Brain Tumor Pathogenesis
- Immune System Cell Regulation of Brain Tumor Pathobiology
- Neuronal Regulation of Brain Tumor Pathobiology
- Self-organization of the Microenvironment Determines Glioma Pathogenesis
- The Brain Microenvironment and Metastasis
- Whole-Brain Resting-State Mapping To Measure The Effect Of Gliomas On Brain Function
6:00 PM – 7:30 PM
Tuesday, October 6, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 1: How to Get More Medical Students to Choose Neurology as a Career
ANA-AUPN Chair Career Level
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ANA-AUPN Chair Career Level
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Course 1: View from the NINDS, NIA, NICHD and the VA
Early (Student, Resident, Trainee, Postdoc Fellow) & Early to Mid-Career Level
Early (Student, Resident, Trainee, Postdoc Fellow) & Early to Mid-Career Level
- Research Opportunities at the NIA
- Research Opportunities at the NICHD
- Research Opportunities at the NINDS
- VA Research Support
11:30 AM – 12:00 PM
12:00 PM – 2:00 PM
Global Neurology
- "Doctor Myself”: Barriers to Effective Diagnosis and Treatment of Zambians with Meningitis
- Asylum-Seekers and Refugees in the U.S.: A Humanitarian Crisis
- Building Research Careers in Global Health: Perspectives from Ghana and the U.S.
- Building Research Careers in Global Health: Perspectives from Ghana and the U.S.
- Characterization of HIV-Associated Neurocognitive Impairment in Older Persons with HIV in Lima, Peru
- Clinician Educators in Global Health: Developing Neurological Care and Training in Zambia
- Clinician Educators in Global Health: Perspectives from Kenya and the U.S.
- Global Health at Home: Underserved Populations in the U.S.
- Global Prevalence of Tuberculosis in the Central Nervous System: A Systematic Review and Meta-Analysis
12:00 PM – 1:15 PM
Recent Advances in Amyloidosis: A Disease You Can't Afford to Miss
- Amyloid Polyneuropathy
- Cerebral Amyloid Angiopathy
- New and Emerging Therapies for Amyloidosis
The Neurology of COVID-19 from Emerging Neurological Infections
- Approaches to Diagnosis and Developing Therapies
- Clinical Features and Lessons from Animal Models
- Epidemiology of the COVID19 Pandemic
Twitter and Social Media: A Role for Neurology and Neuroscience Engagement
- Effective Use of Twitter for Academic Scientists
- Evolving Visual Abstract: Equity in Imagery and Going Live
- eProfessionalism: Ethical and Responsible Use of Social Media
1:45 PM – 2:30 PM
3:00 PM – 5:00 PM
ANA-AHS Headache*
- # Headache: When a Common Problem Becomes a Neurological Emergency in Acute Stroke Patients
- Depression and Migraine - A Double Whammy on Patient-Reported Health
- Migraine Pathophysiology: Focus on Neurovascular Activity and the Sleep-Wake State
- Migraine Treatment: An Update
- New Migraine Therapeutic Targets: The Potential of ASICs and TRP Channels
- Self-Reported Ace Exposure in Adolescents Increases Odds of Frequent Headache: A Cross-Sectional Analysis
Behavioral Neurology
- Autopsy Correlations of Flortaucipir and Pittsburgh Compound B Pet in Frontotemporal Lobar Degeneration
- Early Involvement of Amygdala in Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)
- Eye Movements Abnormalities as Early Biomarker of Alzheimer’s Disease: An Ecological Approach
- Lesion Network Mapping of Mania Symptoms Caused by Focal Brain Lesions
- Selective Vulnerability in Frontotemporal Dementia
- The Upper Motor Neurons with TDP-43 Pathology Display Distinct Cellular Defects
Epilepsy
- AI and Big Data for Critical Care EEG
- Nonconvulsive Status Epilepticus: Evaluation and Treatment
- Utilization of Status Guidelines and Continuous Video EEG Monitoring in the ICU
Neuromuscular Disease
- Characterizing the Histological and Behavioral Phenotypes of a Humanized Knock-In Mouse Modeling a Deep Intronic Mutation in Collagen VI-Related Dystrophy
- Congenital Myopathies: New Advances in Therapy Development
- DNAJB6 Isoform Switching: Mechanistic Insights and Therapeutic Potential for Limb Girdle Muscular Dystrophy 1D
- Immunologic Biomarkers in Autoimmune Neuromuscular Disease
- Machine Learning Optimized Dynamic Meta-analysis to Assess and Predict the Multifactorial Nature of Amyotrophic Lateral Sclerosis
- Neuromuscular Immune Related Adverse Events of Immune Checkpoint Inhibitor Therapies: Towards Risk Mitigation and Targeted Therapies
5:00 PM – 6:00 PM
6:00 PM – 7:30 PM
Wednesday, October 7, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 2: Essential Skills for Academic Productivity in the First 5-10 Years
Early to Mid Career Level
Early to Mid Career Level
- Building Collaborations
- Managing Conflict
- Quantifying Work in Medical Education
- Time Management--Saying No
Course 2: How to Foster Development of Junior Faculty
ANA-AUPN Chair Career Level
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ANA-AUPN Chair Career Level
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Course 2: Skills Development for Success in Research
(Student, Resident, Trainee, Postdoc Fellow) Career Level
(Student, Resident, Trainee, Postdoc Fellow) Career Level
- Being a Good Mentee
- Obtaining Advanced Training
- Writing Effective Manuscripts
11:30 AM – 12:30 PM
12:30 PM – 1:45 PM
Biomarker in Clinical Studies
- Biomarkers in ALS Trials
- Informative Predictive and Prognostic Biomarkers for Neuromuscular Clinical Trials
- Statistical Issues in Biomarker Research
Teleneurology in Academic Practice - Current State and Future Directions
- Future of Teleneurology in Academics
- Incorporation of Telestroke in the Residency Learning Environment
- Teleneurology in Academics: The Nuts and Bolts
The Gene Therapy Toolbox: AAV
- Introduction to AAV as a Delivery Vehicle for Gene Therapy in Neurology
- Lessons from Completed Ongoing AAV Gene Therapy Studies in Parkinson's Disease
- Therapeutic Approaches using AAV: Gene Transfer, Silencing and Editing
2:00 PM – 3:00 PM
Emerging Scholar Lecture 3 (NEW!)
- APOE Genotype Regulates Pathology and Disease Progression in Synucleinopathy
- Cognitive Impairment and Risk Factors of LATE, a Novel Degenerative Pathology
- Critical Glial Role For Parkinson's Disease Risk Genes In Controlling Alpha-synuclein Toxicity
- Disparities in Access to Care and Research Participation in Advanced Parkinson's Disease: Differences Between a Home Visit Study and Outpatient Clinic Population
3:30 PM – 5:30 PM
Multiple Sclerosis*
- Brain Functional Connectivity is Related to Leptomeningeal Enhancement in Relapsing-Remitting Multiple Sclerosis: A 7-T MRI Study
- CNM-Au8: Nanocatalytic Therapy for the Treatment of Chronic Optic Neuropathy
- Neuroimaging Outcomes for Neuroprotection in MS: A Focus on the Retina
- Progressive Multifocal Leukoencephalopathy brain and lesion segmentation from MRI: lessons learnt from deep learning
- Remyelination Alters the Pattern of Myelin in the Cerebral Cortex
- Vascular Comorbidity is Associated with Lower Brain Volumes in a Large Multiple Sclerosis Cohort
Neurocritical Care
- #COVID19: Extraordinary Times call for Extraordinary Measures #InThisTogether
- Global Collaboration on Neurological Impacts of COVID-19
- Multi-objective Control of Learnt Covid-19 Model
- Neurocritical Care in the Era of COVID-19
Traumatic Brain Injury
- Imaging Consciousness: fMRI, Connectomics and the Ascending Arousal Network
- Investigating the Role of the Claustrum in Consciousness Recovery Following Severe Brain Injury
- Lack of Efficacy of Stem Cells in the Treatment of Chemosensory Dysfunction
- Paroxysmal Sympathetic Hyperactivity Syndrome in Severe Traumatic Brain Injury: Patient Characteristics, Utilization of Sedation, Analgesia and Anesthetic Intravenous Infusion Medications and Patient Outcome
- Restoration of Neuronal Function After Coma
- Tapping the Brain of the Comatose with EEG: Impairment and Recovery of Consciousness in the Critical Care Setting
5:30 PM – 6:00 PM
6:00 PM – 7:30 PM
Thursday, October 8, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 3: Critical Decisions in Your Academic Neurology Career
Early to Mid-Career Level
Early to Mid-Career Level
- Navigating Early Career Decisions
- Scholarship Decisions
- Where to Work and When to Move
Course 3: Landing Your Fellowship or First Faculty Position
Early (Student, Resident, Trainee, Postdoc Fellow) Career Level
Early (Student, Resident, Trainee, Postdoc Fellow) Career Level
- Finding Good Fits in Fellowship & Faculty Positions
- Negotiation and Contracts
11:30 AM – 12:30 PM
11:45 AM – 12:15 PM
12:30 PM – 1:45 PM
What Type Of Evidence Should Drive Clinical Decision-Making?
- Can Observational Studies Ever Support Strong Guideline Recommendations?
- Can the Endpoints Measured in Clinical Trials Capture Clinical Meaningfulness?
- Statistical Approaches to the Analysis of Data and limitations
- When RCTs and Real World Evidence Disagree: What Do We Believe?
2:00 PM – 3:00 PM
3:00 PM – 5:00 PM
Autoimmune Neurology
- Beyond the IgG4 antibody subclass in MuSK myasthenia gravis: novel evidence for the pathogenicity of IgG1,2 and 3
- CaVα2δ Autoimmune Encephalitis: A Novel Antibody and Its Characteristics
- Cerebrospinal Fluid Oligoclonal Bands in Anti-NMDA Receptor Encephalitis
- Expanding the Phenotype of Autoimmune Associated Epilepsies
- Natural Language Processing Analyses of Written Text Across Stages of Illness in Anti-NMDA Receptor Encephalitis
- Neuronal Septin Autoimmunity: Differentiated Serological Profiles & Clinical Findings
- Sleep Disorders in Autoimmune Encephalitis
Cerebrovascular Disease & Interventional Neurology
- Corneal Confocal Microscopy: Corneal Nerve Loss In Acute Stroke Patients With Poor Pial Collaterals
- Direct to Angio Suite: The Good, the Bad, and the Evidence
- Post-stroke Dysphagia: Implications & Innovative Therapeutic Approaches
- Racial, Ethnic & Economic Disparities in Stroke Care: The Past & the Future
Dementia and Aging
- Accelerated rate of hippocampal atrophy 17-years prior to death in Alzheimer’s disease is linked to TAR DNA binding protein 43
- Clinical and Research Applications of High Affinity Tau Imaging Agents
- Heterogeneity in Dementia
- History of seizures in Alzheimer’s Disease is associated with elevations in mTOR activity and neuropathology
- Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer’s Disease: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Trial
- Results of the DIAN-TU Prevention Trial of Solanezumab and Ganteneruma
Education
- Authentic Workplace Assessment through the Use of Entrustable Professional Activities
- Competency Based Education - Neurology Subspecialty Fellowship Perspective
- Development of a Database Containing Detail Bedside Neurological Examination and Final Diagnosis
- Improving the Comfortability of Neurology Residents in Providing Care for Spanish-Speaking Monolingual Patients during Neurologic Emergencies
- Measuring Competence Across the Continuum: Beyond the Milestones – Continuing Professional Development
- Simulation for Neurologic Emergencies and Acute Scenarios (SNES) Course: A 4-Year Evolutionary Experience of Utilizing Simulation for Incoming PGY-2 Neurology Residents to Prepare Them for Independent Calls
Health Services Research
- Advances and Challenges of Patient-Reported Outcomes Data to Track and Improve Provider and Patient Experiences
- Increasing Out-of-Pocket Costs for Privately-Insured Neurology Patients
- Interdisciplinary Home Visits for People with Advanced Parkinson's Disease and Related Disorders
- Social Factors Related to Home-Based Telerehabilitation after Stroke
- Teleneurology: A Retrospective
5:15 PM – 6:00 PM
6:00 PM – 7:30 PM
Thursday, October 8, 2020 – Friday, October 9, 2020
10:00 AM – 11:30 AM
Course 3: Managing Up and Down: Getting What You Need From Your Faculty and Your Dean
ANA-AUPN Chair Career Level
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ANA-AUPN Chair Career Level
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Friday, October 9, 2020
8:00 AM – 7:30 PM
10:00 AM – 12:00 PM
12:30 PM – 1:45 PM
Clinical Genetic Testing For Parkinson’s Disease: What, When And How
- Clinical Genetic Testing for Parkinson's Disease: What, When and How
- Counseling and Ethical Issues in Genetic Testing for People with PD and their Family Members
- Overview of PD Genetics: Common Mutations, Variance in Geographic Prevalence and Penetrance
The 2020 NINDS Strategic Plan: A Progress Report and Request for Input
- Opportunities within the NINDS Intramural Program
- Planning Strategically: Ushering Neuroscience Into the Future
2:00 PM – 3:00 PM
Emerging Scholar Lecture 4 (NEW!)
- Gamma Sensory Flicker for Patients with Prodromal Alzheimer’s Disease: A Phase I Trial
- In-vivo Two-photon Imaging Reveals Brain Capillary Plugging During Neurotoxicity in a Mouse Model of Chimeric Antigen Receptor (CAR) T Therapy
- Non-invasive Calcium Imaging Reliably Classifies Sleep States
3:30 PM – 5:30 PM
Movement Disorders
- Altered Capicua Expression Drives Regional Purkinje Neuron Vulnerability Through Ion Channel Gene Dysregulation in Spinocerebellar Ataxia Type 1
- Genetics of PD
- HIV Protease Inhibitors Activate the Integrated Stress Response and Correct Diverse Dystonia Phenotypes in Mouse Models
- Update on Huntington Disease
- Update on Inherited Ataxias
- Variants in Saposin D Domain of Prosaposin Gene are Linked to Parkinson’s Disease
Neuro-Oncology
- Brain Tumor Immunotherapy
- First Dose Pembrolizumab-induced Toxicity in Young Patient Treated for Invasive Thymoma: An Overlap Syndrome of Myasthenia Gravis and Myositis
- Paraneoplastic Syndromes and Neurologic Autoimmunity in the era of Cancer Immunotherapy
- Pre-infusion neurofilament light chain (NfL) levels predict the development of immune effector cell-associated neurotoxicity syndrome (ICANS)
- Update on Car-T Cell Neurotoxicity
Neurogenetics
- A Diagnostic Ceiling for Exome Sequencing in Cerebellar Ataxia and Related Neurological Disorders
- ADNC-RS, a Clinical-Genetic Risk Score, Predicts Alzheimer's Pathology in Autopsy-Confirmed Parkinson's Disease and Dementia with Lewy Bodies
- ALS: Lessons from 10,000 Genomes
- Cell Based Functional Screens to Resolve Genetic Variants
- New Developments in CMT Genetics
Sleep Disorders & Circadian Rhythms
- African-Americans Exhibit Lower Sleep Efficiency and CSF Alzheimer Biomarker Levels Than Non-Hispanic Whites
- Cholinergic innervation of Genioglossus motoneurons in the context of sleep apnea
- Clinical and Genetic Aspects of Human Circadian Phenotypes
- Does Mechanism Matter? Choosing Among Insomnia Treatments
- Take a Nap, Change your Mind: Sleep and Cognition
- The Circadian Protein Bmal1 Mediates Cell Type-Specific Effects on Protein Aggregation and Neuronal Survival in Mouse Models of Synucleinopathy and Tauopathy
5:30 PM – 6:00 PM
6:00 PM – 7:30 PM