Schedule at a Glance

DOWNLOAD SCHEDULE AT A GLANCE

Note: All session times in the Advance Program, Schedule at a Glance, and Program Index are listed in Eastern Daylight Time.
Friday, October 2, 2020
11:00 AM – 4:45 PM
6:00 PM – 7:00 PM
Saturday, October 3, 2020
10:00 AM – 3:00 PM
10:00 AM – 6:00 PM
Translational and Clinical Research Course (TCRC)
Additional registration fee required. Registration for this program has closed.
  • Clinical and Translational Research in Stroke: Model for Innovation and Technology in Design and Conduct
  • Conducting Translational Research in Academia
  • Development of Neurological Therapies: Update from 30,000 Feet
  • Innovations in Design of Clinical Investigations and Trials
  • Keys to Getting Funded Without a K
  • Leading and Utilizing the CTSI
  • Starting and Developing a Successful Career as a Clinical Trialist
  • The Intramural NIH Research Experience
  • The Path to Achieving K-Level Funding
  • Treatments and Guidelines: Paths to Clinical Application
  • Trial Innovation Networks and Multisite Research
7:00 PM – 8:00 PM
Sunday, October 4, 2020
8:00 AM – 9:00 PM
10:00 AM – 12:15 PM
Presidential Symposium: Leveraging Digital Technologies*
  • Deep Phenotyping of Parkinson's Disease Using Digital Technology
  • Developing Novel Outcome Measures for Clinical Trials
  • Digital Therapeutics
  • High-Performance Digital Biomarkers: Ethomic Markers for Rapid, Precise Monitoring of Disease Progression
  • Patient Travel for Neurologist Visits and Implications for Telemedicine: A US Population-based Medicare Study
  • Precision Rehabilitation Strategies for Motor Recovery Post Stroke
12:30 PM – 2:30 PM
Derek Denny-Brown Young Neurological Scholar Symposium
  • Aging, Lysosomes and Neurodegenerative Disease
  • Cerebellar Circuitry of Essential Tremor
  • Dietary Weight Loss May Halt Progression of Polyneuropathy in Patients With Obesity
  • Functional Genomics of Alzheimer's Disease
  • Improving the Diagnostic Precision in Autoimmune Myelopathies and Their Mimics
3:00 PM – 4:00 PM
Emerging Scholar Lectures 1 (NEW!)
  • An Undiagnosed White Matter Disorders Neurogenetics Clinic
  • Loss of Chchd2 and Chchd10 Activates Oma1 Peptidase to Disrupt Mitochondrial Cristae Phenocopying Patient Mutations
  • Objective Dystonia Identification Helps Elucidate Dystonia Pathophysiology
  • The Power of Single Cell Technologies; from T Cell Receptor to Antigen(s) in Multiple Sclerosis
4:30 PM – 6:30 PM
Targeting Glia for Therapy: Mediators of Neuroinflammation, Degeneration and Repair
  • Glia-Mediated Mechanisms of Chemotherapy-Related Cognitive Impairment
  • Kv1.3 Channel Expressing Brain Myeloid Cells are a Unique Pro-inflammatory Subset of Microglia Which Can be Modulated by Kv1.3 Blockers in Alzheimer’s Pathology
  • Oligodendrocyte Precursor Cell Present Antigen and are Cytotoxic Targets in Inflammatory Demyelination
  • Single Nuclei Transcriptomic Profiling of Human Astrocytes in Alzheimer’s Disease and Aging
  • Targeting Microglia-Mediated Synapse Elimination for Therapeutic Intervention in Demyelinating Disease
7:15 PM – 9:00 PM
Monday, October 5, 2020
8:00 AM – 7:30 PM
10:00 AM – 12:00 PM
Genomics of Personalized Medicine
  • CRISPR-Mediated Therapeutics for Duchenne Muscular Dystrophy
  • Genetic Discovery and Translation in Neuromuscular Diseases
  • Genomic Approaches Paving the Way for Precision Neurology
  • Patient-Customized Antisense Therapies for Rare Neurogenetic Diseases
  • Towards Primary Prevention of Genetic Prion Disease
12:15 PM – 1:45 PM
2:00 PM – 3:00 PM
Emerging Scholar Lecture 2 (NEW!)
  • Chemically Patterned Hydrogel Scaffolds Provide Cell-assembled Matrices to Guide Spinal Cord Regeneration
  • FTH1De Novo Dominant Variants Alter Iron Metabolism and Cause a Pediatric Onset Neuroferritinopathy
  • Neuropathy-causing TRPV4 Mutations Disrupt TRPV4-RhoA Interactions and Impair Cytoskeletal Regulation
  • Schwann Cells with Fig4 Deficiency are Predisposed to Demyelination
3:00 PM – 3:30 PM
3:30 PM – 5:45 PM
Microenvironment Control of Brain Tumor Pathogenesis
  • Immune System Cell Regulation of Brain Tumor Pathobiology
  • Neuronal Regulation of Brain Tumor Pathobiology
  • Self-organization of the Microenvironment Determines Glioma Pathogenesis
  • The Brain Microenvironment and Metastasis
  • Whole-Brain Resting-State Mapping To Measure The Effect Of Gliomas On Brain Function
6:00 PM – 7:30 PM
Tuesday, October 6, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 1: View from the NINDS, NIA, NICHD and the VA
Early (Student, Resident, Trainee, Postdoc Fellow) & Early to Mid-Career Level
  • Research Opportunities at the NIA
  • Research Opportunities at the NICHD
  • Research Opportunities at the NINDS
  • VA Research Support
11:30 AM – 12:00 PM
12:00 PM – 2:00 PM
Global Neurology
  • "Doctor Myself”: Barriers to Effective Diagnosis and Treatment of Zambians with Meningitis
  • Asylum-Seekers and Refugees in the U.S.: A Humanitarian Crisis
  • Building Research Careers in Global Health: Perspectives from Ghana and the U.S.
  • Building Research Careers in Global Health: Perspectives from Ghana and the U.S.
  • Characterization of HIV-Associated Neurocognitive Impairment in Older Persons with HIV in Lima, Peru
  • Clinician Educators in Global Health: Developing Neurological Care and Training in Zambia
  • Clinician Educators in Global Health: Perspectives from Kenya and the U.S.
  • Global Health at Home: Underserved Populations in the U.S.
  • Global Prevalence of Tuberculosis in the Central Nervous System: A Systematic Review and Meta-Analysis
12:00 PM – 1:15 PM
Recent Advances in Amyloidosis: A Disease You Can't Afford to Miss
  • Amyloid Polyneuropathy
  • Cerebral Amyloid Angiopathy
  • New and Emerging Therapies for Amyloidosis
The Neurology of COVID-19 from Emerging Neurological Infections
  • Approaches to Diagnosis and Developing Therapies
  • Clinical Features and Lessons from Animal Models
  • Epidemiology of the COVID19 Pandemic
Twitter and Social Media: A Role for Neurology and Neuroscience Engagement
  • Effective Use of Twitter for Academic Scientists
  • Evolving Visual Abstract: Equity in Imagery and Going Live
  • eProfessionalism: Ethical and Responsible Use of Social Media
1:45 PM – 2:30 PM
3:00 PM – 5:00 PM
ANA-AHS Headache*
  • # Headache: When a Common Problem Becomes a Neurological Emergency in Acute Stroke Patients
  • Depression and Migraine - A Double Whammy on Patient-Reported Health
  • Migraine Pathophysiology: Focus on Neurovascular Activity and the Sleep-Wake State
  • Migraine Treatment: An Update
  • New Migraine Therapeutic Targets: The Potential of ASICs and TRP Channels
  • Self-Reported Ace Exposure in Adolescents Increases Odds of Frequent Headache: A Cross-Sectional Analysis
Behavioral Neurology
  • Autopsy Correlations of Flortaucipir and Pittsburgh Compound B Pet in Frontotemporal Lobar Degeneration
  • Early Involvement of Amygdala in Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)
  • Eye Movements Abnormalities as Early Biomarker of Alzheimer’s Disease: An Ecological Approach
  • Lesion Network Mapping of Mania Symptoms Caused by Focal Brain Lesions
  • Selective Vulnerability in Frontotemporal Dementia
  • The Upper Motor Neurons with TDP-43 Pathology Display Distinct Cellular Defects
Epilepsy
  • AI and Big Data for Critical Care EEG
  • Nonconvulsive Status Epilepticus: Evaluation and Treatment
  • Utilization of Status Guidelines and Continuous Video EEG Monitoring in the ICU
Neuromuscular Disease
  • Characterizing the Histological and Behavioral Phenotypes of a Humanized Knock-In Mouse Modeling a Deep Intronic Mutation in Collagen VI-Related Dystrophy
  • Congenital Myopathies: New Advances in Therapy Development
  • DNAJB6 Isoform Switching: Mechanistic Insights and Therapeutic Potential for Limb Girdle Muscular Dystrophy 1D
  • Immunologic Biomarkers in Autoimmune Neuromuscular Disease
  • Machine Learning Optimized Dynamic Meta-analysis to Assess and Predict the Multifactorial Nature of Amyotrophic Lateral Sclerosis
  • Neuromuscular Immune Related Adverse Events of Immune Checkpoint Inhibitor Therapies: Towards Risk Mitigation and Targeted Therapies
5:00 PM – 6:00 PM
6:00 PM – 7:30 PM
Wednesday, October 7, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 2: Essential Skills for Academic Productivity in the First 5-10 Years
Early to Mid Career Level
  • Building Collaborations
  • Managing Conflict
  • Quantifying Work in Medical Education
  • Time Management--Saying No
Course 2: Skills Development for Success in Research
(Student, Resident, Trainee, Postdoc Fellow) Career Level
  • Being a Good Mentee
  • Obtaining Advanced Training
  • Writing Effective Manuscripts
11:30 AM – 12:30 PM
12:30 PM – 1:45 PM
Biomarker in Clinical Studies
  • Biomarkers in ALS Trials
  • Informative Predictive and Prognostic Biomarkers for Neuromuscular Clinical Trials
  • Statistical Issues in Biomarker Research
Teleneurology in Academic Practice - Current State and Future Directions
  • Future of Teleneurology in Academics
  • Incorporation of Telestroke in the Residency Learning Environment
  • Teleneurology in Academics: The Nuts and Bolts
The Gene Therapy Toolbox: AAV
  • Introduction to AAV as a Delivery Vehicle for Gene Therapy in Neurology
  • Lessons from Completed Ongoing AAV Gene Therapy Studies in Parkinson's Disease
  • Therapeutic Approaches using AAV: Gene Transfer, Silencing and Editing
2:00 PM – 3:00 PM
Emerging Scholar Lecture 3 (NEW!)
  • APOE Genotype Regulates Pathology and Disease Progression in Synucleinopathy
  • Cognitive Impairment and Risk Factors of LATE, a Novel Degenerative Pathology
  • Critical Glial Role For Parkinson's Disease Risk Genes In Controlling Alpha-synuclein Toxicity
  • Disparities in Access to Care and Research Participation in Advanced Parkinson's Disease: Differences Between a Home Visit Study and Outpatient Clinic Population
3:30 PM – 5:30 PM
Multiple Sclerosis*
  • Brain Functional Connectivity is Related to Leptomeningeal Enhancement in Relapsing-Remitting Multiple Sclerosis: A 7-T MRI Study
  • CNM-Au8: Nanocatalytic Therapy for the Treatment of Chronic Optic Neuropathy
  • Neuroimaging Outcomes for Neuroprotection in MS: A Focus on the Retina
  • Progressive Multifocal Leukoencephalopathy brain and lesion segmentation from MRI: lessons learnt from deep learning
  • Remyelination Alters the Pattern of Myelin in the Cerebral Cortex
  • Vascular Comorbidity is Associated with Lower Brain Volumes in a Large Multiple Sclerosis Cohort
Neurocritical Care
  • #COVID19: Extraordinary Times call for Extraordinary Measures #InThisTogether
  • Global Collaboration on Neurological Impacts of COVID-19
  • Multi-objective Control of Learnt Covid-19 Model
  • Neurocritical Care in the Era of COVID-19
Traumatic Brain Injury
  • Imaging Consciousness: fMRI, Connectomics and the Ascending Arousal Network
  • Investigating the Role of the Claustrum in Consciousness Recovery Following Severe Brain Injury
  • Lack of Efficacy of Stem Cells in the Treatment of Chemosensory Dysfunction
  • Paroxysmal Sympathetic Hyperactivity Syndrome in Severe Traumatic Brain Injury: Patient Characteristics, Utilization of Sedation, Analgesia and Anesthetic Intravenous Infusion Medications and Patient Outcome
  • Restoration of Neuronal Function After Coma
  • Tapping the Brain of the Comatose with EEG: Impairment and Recovery of Consciousness in the Critical Care Setting
5:30 PM – 6:00 PM
6:00 PM – 7:30 PM
Thursday, October 8, 2020
8:00 AM – 7:30 PM
10:00 AM – 11:30 AM
Course 3: Critical Decisions in Your Academic Neurology Career
Early to Mid-Career Level
  • Navigating Early Career Decisions
  • Scholarship Decisions
  • Where to Work and When to Move
Course 3: Landing Your Fellowship or First Faculty Position
Early (Student, Resident, Trainee, Postdoc Fellow) Career Level
  • Finding Good Fits in Fellowship & Faculty Positions
  • Negotiation and Contracts
11:30 AM – 12:30 PM
11:45 AM – 12:15 PM
12:30 PM – 1:45 PM
What Type Of Evidence Should Drive Clinical Decision-Making?
  • Can Observational Studies Ever Support Strong Guideline Recommendations?
  • Can the Endpoints Measured in Clinical Trials Capture Clinical Meaningfulness?
  • Statistical Approaches to the Analysis of Data and limitations
  • When RCTs and Real World Evidence Disagree: What Do We Believe?
2:00 PM – 3:00 PM
3:00 PM – 5:00 PM
Autoimmune Neurology
  • Beyond the IgG4 antibody subclass in MuSK myasthenia gravis: novel evidence for the pathogenicity of IgG1,2 and 3
  • CaVα2δ Autoimmune Encephalitis: A Novel Antibody and Its Characteristics
  • Cerebrospinal Fluid Oligoclonal Bands in Anti-NMDA Receptor Encephalitis
  • Expanding the Phenotype of Autoimmune Associated Epilepsies
  • Natural Language Processing Analyses of Written Text Across Stages of Illness in Anti-NMDA Receptor Encephalitis
  • Neuronal Septin Autoimmunity: Differentiated Serological Profiles & Clinical Findings
  • Sleep Disorders in Autoimmune Encephalitis
Cerebrovascular Disease & Interventional Neurology
  • Corneal Confocal Microscopy: Corneal Nerve Loss In Acute Stroke Patients With Poor Pial Collaterals
  • Direct to Angio Suite: The Good, the Bad, and the Evidence
  • Post-stroke Dysphagia: Implications & Innovative Therapeutic Approaches
  • Racial, Ethnic & Economic Disparities in Stroke Care: The Past & the Future
Dementia and Aging
  • Accelerated rate of hippocampal atrophy 17-years prior to death in Alzheimer’s disease is linked to TAR DNA binding protein 43
  • Clinical and Research Applications of High Affinity Tau Imaging Agents
  • Heterogeneity in Dementia
  • History of seizures in Alzheimer’s Disease is associated with elevations in mTOR activity and neuropathology
  • Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer’s Disease: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Trial
  • Results of the DIAN-TU Prevention Trial of Solanezumab and Ganteneruma
Education
  • Authentic Workplace Assessment through the Use of Entrustable Professional Activities
  • Competency Based Education - Neurology Subspecialty Fellowship Perspective
  • Development of a Database Containing Detail Bedside Neurological Examination and Final Diagnosis
  • Improving the Comfortability of Neurology Residents in Providing Care for Spanish-Speaking Monolingual Patients during Neurologic Emergencies
  • Measuring Competence Across the Continuum: Beyond the Milestones – Continuing Professional Development
  • Simulation for Neurologic Emergencies and Acute Scenarios (SNES) Course: A 4-Year Evolutionary Experience of Utilizing Simulation for Incoming PGY-2 Neurology Residents to Prepare Them for Independent Calls
Health Services Research
  • Advances and Challenges of Patient-Reported Outcomes Data to Track and Improve Provider and Patient Experiences
  • Increasing Out-of-Pocket Costs for Privately-Insured Neurology Patients
  • Interdisciplinary Home Visits for People with Advanced Parkinson's Disease and Related Disorders
  • Social Factors Related to Home-Based Telerehabilitation after Stroke
  • Teleneurology: A Retrospective
5:15 PM – 6:00 PM
6:00 PM – 7:30 PM
Thursday, October 8, 2020 – Friday, October 9, 2020
Friday, October 9, 2020
8:00 AM – 7:30 PM
10:00 AM – 12:00 PM
12:30 PM – 1:45 PM
Clinical Genetic Testing For Parkinson’s Disease: What, When And How
  • Clinical Genetic Testing for Parkinson's Disease: What, When and How
  • Counseling and Ethical Issues in Genetic Testing for People with PD and their Family Members
  • Overview of PD Genetics: Common Mutations, Variance in Geographic Prevalence and Penetrance
The 2020 NINDS Strategic Plan: A Progress Report and Request for Input
  • Opportunities within the NINDS Intramural Program
  • Planning Strategically: Ushering Neuroscience Into the Future
2:00 PM – 3:00 PM
Emerging Scholar Lecture 4 (NEW!)
  • Gamma Sensory Flicker for Patients with Prodromal Alzheimer’s Disease: A Phase I Trial
  • In-vivo Two-photon Imaging Reveals Brain Capillary Plugging During Neurotoxicity in a Mouse Model of Chimeric Antigen Receptor (CAR) T Therapy
  • Non-invasive Calcium Imaging Reliably Classifies Sleep States
3:30 PM – 5:30 PM
Movement Disorders
  • Altered Capicua Expression Drives Regional Purkinje Neuron Vulnerability Through Ion Channel Gene Dysregulation in Spinocerebellar Ataxia Type 1
  • Genetics of PD
  • HIV Protease Inhibitors Activate the Integrated Stress Response and Correct Diverse Dystonia Phenotypes in Mouse Models
  • Update on Huntington Disease
  • Update on Inherited Ataxias
  • Variants in Saposin D Domain of Prosaposin Gene are Linked to Parkinson’s Disease
Neuro-Oncology
  • Brain Tumor Immunotherapy
  • First Dose Pembrolizumab-induced Toxicity in Young Patient Treated for Invasive Thymoma: An Overlap Syndrome of Myasthenia Gravis and Myositis
  • Paraneoplastic Syndromes and Neurologic Autoimmunity in the era of Cancer Immunotherapy
  • Pre-infusion neurofilament light chain (NfL) levels predict the development of immune effector cell-associated neurotoxicity syndrome (ICANS)
  • Update on Car-T Cell Neurotoxicity
Neurogenetics
  • A Diagnostic Ceiling for Exome Sequencing in Cerebellar Ataxia and Related Neurological Disorders
  • ADNC-RS, a Clinical-Genetic Risk Score, Predicts Alzheimer's Pathology in Autopsy-Confirmed Parkinson's Disease and Dementia with Lewy Bodies
  • ALS: Lessons from 10,000 Genomes
  • Cell Based Functional Screens to Resolve Genetic Variants
  • New Developments in CMT Genetics
Sleep Disorders & Circadian Rhythms
  • African-Americans Exhibit Lower Sleep Efficiency and CSF Alzheimer Biomarker Levels Than Non-Hispanic Whites
  • Cholinergic innervation of Genioglossus motoneurons in the context of sleep apnea
  • Clinical and Genetic Aspects of Human Circadian Phenotypes
  • Does Mechanism Matter? Choosing Among Insomnia Treatments
  • Take a Nap, Change your Mind: Sleep and Cognition
  • The Circadian Protein Bmal1 Mediates Cell Type-Specific Effects on Protein Aggregation and Neuronal Survival in Mouse Models of Synucleinopathy and Tauopathy
5:30 PM – 6:00 PM
6:00 PM – 7:30 PM